Oncogenomics is a subfield of genomics characterizing the genes that cause cancer. Three genes that are primarily responsible for cancer development are
i) Oncogenes- In the case of cancer, these genes replace the protooncogenes responsible for normal cell growth and make the cells grow and divide rapidly forming cancer.
ii) Tumor suppressor genes – In a cancerous patient, the tumor suppressor genes that inhibit cell division gets turned off and thus leading to the uncontrolled division of cells which further results in cancer
iii) DNA repair genes –DNA mutations or damages in DNA are repaired and controlled by these genes. A healthy cell turns into a cancerous one when these DNA repair genes get disabled or altered.
- Track 1-1 Cancer associated genes
- Track 2-2 Oncogenes
- Track 3-3 Tumor Suppressor Genes
- Track 4-4 DNA repair genes